CENTRAL VICE CONTROL SECTION, commanded by a captain, is responsible for activity related to general vice and drug enforcement. The section enforces laws related to liquor, prostitution, gambling, drugs, obscenity, pornography and regulatory violations. The section operates two shifts, each commanded by a lieutenant. A drug dog is assigned to each of these shifts. The section coordinates Department enforcement activity in these areas and provides a central repository for related records and vice intelligence information. In addition to street level drug and vice enforcement, the section also includes the Regional Enforcement Narcotics Unit (RENU), a unit focusing on mid-level drug dealers, and the Regulatory Enforcement Unit.

• Regional Enforcement Narcotics Unit, supervised by a sergeant, has personnel assigned to the Regional Enforcement Narcotics Unit (RENU). RENU is a multi-agency organization which investigates primary sources for the suppliers of illicit drugs into Greater Cincinnati.
  
• Mid-Level Drug Unit, commanded by a sergeant, is responsible for undercover personnel assigned to investigate mid-level drug activity. This unit includes Asset Forfeiture.
  
• Regulatory Enforcement Unit, supervised by a sergeant, has primary responsibility for oversight of investigations into four areas. These areas are Pharmaceutical Compliance, Asset Forfeiture, Liquor Control and Drug Abatement.