300-302, 304-306 Main Street, and 208-210 E. 3rd Street (Central Business District)
Significance: This cluster is composed of six significant late 19th and early 20th century buildings exhibiting distinctive architectural characteristics and styles associated with their period of construction as applied to commercial use. Their scale, location, materials, and setting produced a grouping that is both cohesive in design, feeling, and association and visually distinct from its surroundings. The area once housed the University of Cincinnati’s McMicken School of Design and the offices of Salmon B. Chase, Supreme Court Justice and President Lincoln’s Secretary of the Treasury.
